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The delay in approving the Oxford vaccine is beginning to worry me, the longer it goes on the more I wonder if they have found something amiss.

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3 hours ago, CANARYKING said:

The delay in approving the Oxford vaccine is beginning to worry me, the longer it goes on the more I wonder if they have found something amiss.

I was told last week it was all to do with age group data and the half vaccine effect data, It should be approved by 28th. But again only third party info nothing official.

Edited by Indy

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Another article from a trade paper suggesting Oxford to be used in care homes. I am finding that surprising as I thought the problem would be the over 55’s but shows after all these months can still be wrong assuming these latest reports are correct.

https://www.carehomeprofessional.com/oxford-jab-approval-will-speed-up-care-home-vaccinations-says-gps-leader/

 

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30 minutes ago, Well b back said:

Another article from a trade paper suggesting Oxford to be used in care homes. I am finding that surprising as I thought the problem would be the over 55’s but shows after all these months can still be wrong assuming these latest reports are correct.

https://www.carehomeprofessional.com/oxford-jab-approval-will-speed-up-care-home-vaccinations-says-gps-leader/

 

WBB I think it shows that full data was still being evaluated, now we’re seeing the full details, it looks as though it’s the same immunity in most ages. Good news for us and the rest of the world as it’s cheap and easy to produce.

Just hope it can reduce the spread and has longevity once administered.

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Just now, Indy said:

WBB I think it shows that full data was still being evaluated, now we’re seeing the full details, it looks as though it’s the same immunity in most ages. Good news for us and the rest of the world as it’s cheap and easy to produce.

Just hope it can reduce the spread and has longevity once administered.

Spot on.

It just goes to show that based on what we see, there is always another story once the data is looked into by the experts. It will be amazing if it is immediately approved for the over 55’s as well.

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9 minutes ago, Indy said:

WBB I think it shows that full data was still being evaluated, now we’re seeing the full details, it looks as though it’s the same immunity in most ages. Good news for us and the rest of the world as it’s cheap and easy to produce.

Just hope it can reduce the spread and has longevity once administered.

Should have also said if approved next week I have no worries about it’s efficiency against the mutations as Oxford it was who reported them in September so they must have already done their computer simulations.

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2 minutes ago, Well b back said:

Should have also said if approved next week I have no worries about it’s efficiency against the mutations as Oxford it was who reported them in September so they must have already done their computer simulations.

We can only hope, but lots of scientists are saying the vaccines will have full efficiency already stated. So I’m not too worried, just want it approved and started.

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Mixed in all that s*** Matt Hancock said

  • The Oxford-AstraZeneca vaccine has submitted its full data package to the MHRA for approval

It would seem therefore that the 28th / 29th is likely to be our date.

Hopefully our story is coming to an end soon.

 

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30 minutes ago, Well b back said:

Mixed in all that s*** Matt Hancock said

  • The Oxford-AstraZeneca vaccine has submitted its full data package to the MHRA for approval

It would seem therefore that the 28th / 29th is likely to be our date.

Hopefully our story is coming to an end soon.

 

Hope so.

I would love to know what the plan is to roll out the vaccine to the masses. It's clear from recent trends that this is a BIG ticket item for getting back to some form of normality. The current rate of vaccinations is way too slow.

What is the daily goal when we move to mass vaccinations, 1mill/day? 1.5m, 2m.....???

If it was 1m/day then everyone could be done by Easter 2021.

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1 minute ago, SteveN8458 said:

Hope so.

I would love to know what the plan is to roll out the vaccine to the masses. It's clear from recent trends that this is a BIG ticket item for getting back to some form of normality. The current rate of vaccinations is way too slow.

What is the daily goal when we move to mass vaccinations, 1mill/day? 1.5m, 2m.....???

If it was 1m/day then everyone could be done by Easter 2021.

The mass centres as we understand on it on here are ready to rock and roll. You are right in that huge numbers could be vaccinated but at first it will be quantity of the vaccine. After saying that it appears that we have 4 million doses ready to go and some of the manufacture will be in the U.K. Huge amounts are being produced in India and we can only assume they are producing on mass even whilst approval is still not yet here.

Of course the two proviso’s are who they can use it on ( although reports in the last few days have suggested ok in the over 55’s ) and if it works on the new variant, but of course Oxford and AstraZeneca have said in the last few days ‘ it is highly likely ‘ it will and have had the new variant on their computers since September. We can only again assume that the South African variant is also known to Oxford as there are ongoing trials there.

Hopefully not long till we get the answers now. 

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17 hours ago, Well b back said:

The mass centres as we understand on it on here are ready to rock and roll. You are right in that huge numbers could be vaccinated but at first it will be quantity of the vaccine. After saying that it appears that we have 4 million doses ready to go and some of the manufacture will be in the U.K. Huge amounts are being produced in India and we can only assume they are producing on mass even whilst approval is still not yet here.

Of course the two proviso’s are who they can use it on ( although reports in the last few days have suggested ok in the over 55’s ) and if it works on the new variant, but of course Oxford and AstraZeneca have said in the last few days ‘ it is highly likely ‘ it will and have had the new variant on their computers since September. We can only again assume that the South African variant is also known to Oxford as there are ongoing trials there.

Hopefully not long till we get the answers now. 

I read today that they are looking at only one jab of the Pfizer as it is 91% effective.

https://uk.yahoo.com/news/people-one-vaccine-dose-race-103935857.html

 

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7 minutes ago, SteveN8458 said:

I read today that they are looking at only one jab of the Pfizer as it is 91% effective.

https://uk.yahoo.com/news/people-one-vaccine-dose-race-103935857.html

 

Unfortunately with no medical experience Blair made this comment. That data has never been studied but it is believed one dose would be under 50 % effective and nobody would now how long even that would last.

There was a good article I read last night I will get it up for you this afternoon.

Hope that doesn’t sound negative just I can’t see it happening.

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While your here WBB, do you have any definitive information regarding the amount (if any) of the Oxford vaccine we have ready to go?

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40 minutes ago, Daz Sparks said:

While your here WBB, do you have any definitive information regarding the amount (if any) of the Oxford vaccine we have ready to go?

I will look up to be more accurate but my understanding 

4 million produced in the U.K. ready by the end of the year ( so I assume that rolls to when it is approved ).

We have then ordered 100 million more doses ( which I believe will mainly come from India but clearly our production will also increase ) of which we have been promised 40 million by Spring. 

Now Pfizer is a different matter as if I have got it right we were promised 800,000 ( that appears to have gone to a million ) by the end of the year. Now if those figures are correct and the government figures are correct at 500,000 vaccinations to date we have run out of our initial allocation so not exactly sure when our next batch is coming as Europe are due to start straight after Christmas so have a huge allocation.

We are not due any Moderna doses until Spring, but my believe is that was a bit of a publicity stunt because it worked.

Of course we do have to wait and see if Oxford will be approved in all age groups, but the noises coming out of Oxford have been quite good that it can be used on the over 55’s

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1 hour ago, SteveN8458 said:

I read today that they are looking at only one jab of the Pfizer as it is 91% effective.

https://uk.yahoo.com/news/people-one-vaccine-dose-race-103935857.html

 

Hi again Steve

I can never absolutely guarantee % but here are the initial official efficacy reports ( from the 11/12 ) and an article from yesterday which questions what was said. Certainly can’t see it happening before ( fingers crossed ) Oxford is approved. My understanding as well ( and I will stand to be corrected ) is that if you had 1 and then a second 1 a long time later, you would then need a third one and that’s not good at £20 - £30 a pop. As always I am happy to be corrected if somebody knows more.

https://www.bmj.com/content/371/bmj.m4826

https://www.theguardian.com/world/2020/dec/23/more-data-needed-before-second-vaccine-dose-diverted-to-first-timers-says-covid-adviser

 

 

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1 hour ago, Daz Sparks said:

While your here WBB, do you have any definitive information regarding the amount (if any) of the Oxford vaccine we have ready to go?

Hope this helps. Pfizer is being used for political point scoring so it is hard to know what we are getting. The quotes below are from different articles. Hope that helps

The Department of Health and Social Care said the UK would be one of the first countries in the world to receive the vaccine, if it was authorised, with AstraZeneca set to have as many as 4 million doses ready for the UK by the end of the year and 40 million by the end of March 2021.

The government has ordered 100 million doses of the Oxford/AstraZeneca vaccine, with around 40 million due to be available by the end of March.

Upon approval, a major operation will swing into action to distribute the vaccine from storage facilities to countries around the world. Here, the Oxford vaccine has an advantage. Two other frontrunner vaccines, from Pfizer/BioNTech and the US National Institutes of Health/Moderna, must be stored at ultra-low temperatures until shortly before they are used. This makes distribution of the shots a formidable challenge in some parts of the world. The Oxford vaccine isn’t as fragile and can be stored for long periods at 2C to 4C, or standard refrigeration temperatures. The Oxford vaccine is much cheaper too: about one-tenth of the cost of the other two.

 

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20 hours ago, SteveN8458 said:

Hope so.

I would love to know what the plan is to roll out the vaccine to the masses. It's clear from recent trends that this is a BIG ticket item for getting back to some form of normality. The current rate of vaccinations is way too slow.

What is the daily goal when we move to mass vaccinations, 1mill/day? 1.5m, 2m.....???

If it was 1m/day then everyone could be done by Easter 2021.

Its over 90 days until easter.  We could do it at half that rate and still have a 2019 Easter break. 

I might even look at booking a holiday the minute the jab is approved!

Edited by Barbe bleu

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21 hours ago, SteveN8458 said:

Hope so.

I would love to know what the plan is to roll out the vaccine to the masses. It's clear from recent trends that this is a BIG ticket item for getting back to some form of normality. The current rate of vaccinations is way too slow.

What is the daily goal when we move to mass vaccinations, 1mill/day? 1.5m, 2m.....???

If it was 1m/day then everyone could be done by Easter 2021.

But we don't need everybody done, as I understand it, around 50% should pretty much end the crisis.

 

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5 hours ago, Well b back said:

Unfortunately with no medical experience Blair made this comment. That data has never been studied but it is believed one dose would be under 50 % effective and nobody would now how long even that would last.

There was a good article I read last night I will get it up for you this afternoon.

Hope that doesn’t sound negative just I can’t see it happening.

it was done on the wooly presumption that 91% effectiveness was reached by day 7 of second dose and therefore before the 2nd dose had any time to take effect.

It's a fair thought but a pretty terrible idea in practice. Vaccines don't just work like that and realistically, the main vulnerable group should remain the priority for the double dose, anything else would be far too chaotic. Perhaps it is food for thought for later on next year when we look at mass immunisation of the rest of us though.

One personal anecdote this year, we were looking after a puppy for a vulnerable relative who had been for his first jab and we were told the wrong date for jab 2 which was supposed to be 3 weeks later with a 1 week stability window. Because we missed the window, the poor little scamp had to start again so had to go back for a 3rd dose 3 weeks later before he was allowed to go for walks and socialise. Best to stick with the proven dose regimen!

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1 hour ago, Mark .Y. said:

But we don't need everybody done, as I understand it, around 50% should pretty much end the crisis.

 

depends on transmission but yeah, 50% of the most vulnerable/susceptible should suffice.

It might even be less than that, if you look at the hospitalisations, it's overwhelmingly the elderly and vulnerable 10%. If these people are vaccinated then hospitalisations will ease but we'll be in a rocky catch 22 of wanting to get back to normal while there is still a susceptible population that, while perhaps they won't die or need hospital, they could get a bad dose of covid that has some longer term ramifications that most would rather avoid. Add to that the problems with mutation threats etc. and it's gonna be a rocky but hopefully much better 2021.

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Hi Everyone

I suspect now we won’t be getting Oxford as a Christmas present, but still hopeful that next week will see the end of our story. Therefore may I take this opportunity to wish everybody a very Merry Christmas.

 

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1 hour ago, Well b back said:

Hi Everyone

I suspect now we won’t be getting Oxford as a Christmas present, but still hopeful that next week will see the end of our story. Therefore may I take this opportunity to wish everybody a very Merry Christmas.

 

You too Wbb

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3 minutes ago, sonyc said:

https://www.mirror.co.uk/news/politics/oxford-coronavirus-vaccine-to-rolled-23225009?utm_source=linkCopy&utm_medium=social&utm_campaign=sharebar

Roll out indicated from the 4th January ...this article just appeared in last few minutes

 

 

Yep I think everything is looking good Monday or Tuesday. I am that little bit more confident as well as the last bits of data arrived earlier in the week and had there have been some bad news, Boris could have let that slip during his victory parade. 

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